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The antibody against ELK4 was raised in rabbit using the Human ELK4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against ELK4 was raised in rabbit using the Human ELK4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-53461A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ELK4 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human ELK4 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P28324 |
Uniprot Id
P28324
Target Species
Human
Target Name
ELK4
Target Full Name
ETS domain-containing protein Elk-4
Target Function
Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18' (H3K18Ac) and subsequent transcription repression. Forms a ternary complex with the serum response factor (SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously.
Target Subcellular Location
Nucleus.
Target Protein Families
ETS family
Target Synonyms
Elk4; ELK4_HUMAN; ETS domain containing protein Elk4; ETS domain protein; ETS domain-containing protein Elk-4; SAP-1; SAP1; Serum response factor accessory protein 1; SRF accessory protein 1; TCF1
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