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The antibody against EMB was raised in rabbit using the Recombinant Human Embigin protein (285-327AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against EMB was raised in rabbit using the Recombinant Human Embigin protein (285-327AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human small intestine tissue using EMB Antibody at dilution of 1:1002
| Cat.No | ADC-10346A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EMB |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Embigin protein (285-327AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6PCB8 |
Uniprot Id
Q6PCB8
Target Species
Human
Target Name
EMB
Target Full Name
Embigin
Target Function
Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cell junction, synapse.
Target Synonyms
Emb; EMB_HUMAN; Embigin; Embigin homolog (mouse); embigin homolog; MGC71745; OTTHUMP00000161812; OTTHUMP00000221477; OTTHUMP00000221478; OTTHUMP00000221479
Target Background
This gene encodes a transmembrane glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1.
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