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The antibody against EMC9 was raised in rabbit using the Recombinant Human ER membrane protein complex subunit 9 protein (1-208AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against EMC9 was raised in rabbit using the Recombinant Human ER membrane protein complex subunit 9 protein (1-208AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-44846A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EMC9 |
| Target Synonyms | EMC9 antibody; C14orf122 antibody; FAM158A antibody; CGI-112 antibody; ER membrane protein complex subunit 9 antibody; Protein FAM158A antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human ER membrane protein complex subunit 9 protein (1-208AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y3B6 |
Uniprot Id
Q9Y3B6
Target Species
Human
Target Name
EMC9
Target Full Name
ER membrane protein complex subunit 9
Target Function
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors. By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable).
Target Subcellular Location
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
EMC8/EMC9 family
Target Research Area
Signal Transduction
Target Synonyms
EMC9; C14orf122; FAM158A; CGI-112; ER membrane protein complex subunit 9; Protein FAM158A
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