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The antibody against EPN2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Epsin 2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against EPN2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Epsin 2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
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Western Blot analysis of HuvEc cells using Epsin 2 Polyclonal Antibody
| Cat.No | ADC-38725A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EPN2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human Epsin 2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O95208 |
Uniprot Id
O95208
Target Species
Human
Target Name
EPN2
Target Full Name
Epsin-2
Target Function
Plays a role in the formation of clathrin-coated invaginations and endocytosis.
Target Subcellular Location
Cytoplasm. Cytoplasmic vesicle, clathrin-coated vesicle. Note=In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.
Target Protein Families
Epsin family
Target Tissue Specificity
Highest expression is found in brain. Detected at lower levels in lung and liver.
Target Synonyms
EHB21; EPN 2; Epn2; EPN2_HUMAN; EPS 15 interacting protein 2; EPS-15-interacting protein 2; Eps15 binding protein; Epsin 2; Epsin-2; Epsin2; KIAA1065; OTTHUMP00000065808; OTTHUMP00000065809; OTTHUMP00000065810; OTTHUMP00000065811; OTTHUMP00000065889
Target Background
Predicted to enable clathrin binding activity and phospholipid binding activity. Acts upstream of or within Notch signaling pathway; embryonic organ development; and in utero embryonic development. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of clathrin coat of endocytic vesicle. Predicted to be active in endosome and plasma membrane. Orthologous to human EPN2 (epsin 2).
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