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The antibody against FBXO28 was raised in rabbit using the Recombinant Human F-box only protein 28 protein (251-368AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against FBXO28 was raised in rabbit using the Recombinant Human F-box only protein 28 protein (251-368AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human kidney tissue using FBXO28 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using FBXO28 Antibody at dilution of 1:1002
| Cat.No | ADC-17835A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FBXO28 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human F-box only protein 28 protein (251-368AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NVF7 |
Uniprot Id
Q9NVF7
Target Species
Human
Target Name
FBXO28
Target Full Name
F-box only protein 28
Target Function
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
Target Subcellular Location
Chromosome, centromere, kinetochore.
Target Synonyms
CENP 30; Centromere protein 30; F box only protein 28; F box protein 28; F-box only protein 28; Fbx28 ; FBX28_HUMAN; FBXO28; FLJ10766; KIAA0483; OTTHUMP00000035597
Target Background
Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
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