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The antibody against GINS4 was raised in rabbit using the Recombinant Human DNA replication complex GINS protein SLD5 protein (2-223AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against GINS4 was raised in rabbit using the Recombinant Human DNA replication complex GINS protein SLD5 protein (2-223AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human skin tissue using GINS4 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using GINS4 Antibody at dilution of 1:1002
| Cat.No | ADC-18257A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GINS4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human DNA replication complex GINS protein SLD5 protein (2-223AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BRT9 |
Uniprot Id
Q9BRT9
Target Species
Human
Target Name
GINS4
Target Full Name
DNA replication complex GINS protein SLD5
Target Function
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA.
Target Subcellular Location
Nucleus. Chromosome. Cytoplasm.
Target Protein Families
GINS4/SLD5 family
Target Synonyms
DNA replication complex GINS protein SLD5; GINS complex subunit 4 (Sld5 homolog); GINS complex subunit 4; GINS4; SLD5; SLD5 homolog; SLD5 S cerevisiae homolog of; SLD5_HUMAN
Target Background
The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.
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