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Rabbit anti-Human GJB2 Polyclonal Antibody

The antibody against GJB2 was raised in rabbit using the Human Connexin-26 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-46620A

The antibody against GJB2 was raised in rabbit using the Human Connexin-26 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-46620A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGJB2
Target SynonymsGJB2; Gap junction beta-2 protein; Connexin-26; Cx26FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman Connexin-26Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP29033
Background Information
  • Uniprot Id

    P29033

  • Target Species

    Human

  • Target Name

    GJB2

  • Target Full Name

    Gap junction beta-2 protein

  • Target Function

    Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.

  • Target Involvement

    Deafness, autosomal recessive, 1A (DFNB1A); Deafness, autosomal dominant, 3A (DFNA3A); Vohwinkel syndrome (VOWNKL); Keratoderma, palmoplantar, with deafness (PPKDFN); Keratitis-ichthyosis-deafness syndrome (KID syndrome); Bart-Pumphrey syndrome (BPS); Ichthyosis hystrix-like with deafness syndrome (HID syndrome)

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

  • Target Protein Families

    Connexin family, Beta-type (group I) subfamily

  • Target Synonyms

    GJB2; Gap junction beta-2 protein; Connexin-26; Cx26

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