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Rabbit anti-Human GK Polyclonal Antibody

The antibody against GK was raised in rabbit using the Synthesized peptide derived from C-terminal of Human GLPK. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IF.

ADC-42083A

The antibody against GK was raised in rabbit using the Synthesized peptide derived from C-terminal of Human GLPK. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IF.

$297.00

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Specifications


Cat.No ADC-42083A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGK
FormLiquidSpecies ReactivityHuman, Mouse, Rat
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, IF, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from C-terminal of Human GLPK.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP32189
Background Information
  • Uniprot Id

    P32189

  • Target Species

    Human

  • Target Name

    GK

  • Target Full Name

    Glycerol kinase

  • Target Function

    Key enzyme in the regulation of glycerol uptake and metabolism.

  • Target Involvement

    Glycerol kinase deficiency (GKD)

  • Target Subcellular Location

    Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm.

  • Target Protein Families

    FGGY kinase family

  • Target Tissue Specificity

    Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.

  • Target Synonyms

    ATP glycerol 3 phosphotransferase; ATP:glycerol 3 phosphotransferase; ATP:glycerol 3-phosphotransferase; D930012N15Rik; GK; GK1; GKD; GLPK_HUMAN; Glycerokinase; Glycerol kinase; OTTHUMP00000023108; OTTHUMP00000023109; OTTHUMP00000215321

  • Target Background

    The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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