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The antibody against GPX7 was raised in rabbit using the Recombinant Human Glutathione peroxidase 7 protein (28-187AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against GPX7 was raised in rabbit using the Recombinant Human Glutathione peroxidase 7 protein (28-187AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human liver cancer using GPX7 Antibody at dilution of 1:100
| Cat.No | ADC-24784A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GPX7 |
| Target Synonyms | CL683 antibody; FLJ14777 antibody; Glutathione peroxidase 7 antibody; GPx-7 antibody; GPX6 antibody; GPX7 antibody; GPX7_HUMAN antibody; GSHPx-7 antibody; NPGPx antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Glutathione peroxidase 7 protein (28-187AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96SL4 |
Uniprot Id
Q96SL4
Target Species
Human
Target Name
GPX7
Target Full Name
Glutathione peroxidase 7
Target Function
It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks.
Target Involvement
Barrett esophagus (BE)
Target Subcellular Location
Secreted.
Target Protein Families
Glutathione peroxidase family
Target Tissue Specificity
Expressed in esophageal epithelial cells; expression is up-regulated after exposure to acidic bile acids.
Target Synonyms
CL683; FLJ14777; Glutathione peroxidase 7; GPx-7; GPX6; GPX7; GPX7_HUMAN; GSHPx-7; NPGPx
Target Background
Enables catalase activity. Predicted to be involved in cellular response to oxidative stress. Located in endoplasmic reticulum.
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