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The antibody against GRIN3B was raised in rabbit using the Recombinant Human Glutamate receptor ionotropic, NMDA 3B protein (180-410AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
The antibody against GRIN3B was raised in rabbit using the Recombinant Human Glutamate receptor ionotropic, NMDA 3B protein (180-410AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-16353A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GRIN3B |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Glutamate receptor ionotropic, NMDA 3B protein (180-410AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60391 |
Uniprot Id
O60391
Target Species
Human
Target Name
GRIN3B
Target Full Name
Glutamate receptor ionotropic, NMDA 3B
Target Function
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane.
Target Protein Families
Glutamate-gated ion channel (TC 1.A.10.1) family, NR3B/GRIN3B subfamily
Target Synonyms
GluN3B; Glutamate [NMDA] receptor subunit 3B; Glutamate receptor ionotropic N methyl D aspartate 3B ; Glutamate receptor ionotropic NMDA 3B; GRIN3B; N-methyl-D-aspartate receptor subtype 3B; NMD3B_HUMAN; NMDA receptor subunit 3B; NMDA type glutamate receptor subunit NR3B; NMDAR3B; NR3B
Target Background
The protein encoded by this gene is a subunit of an N-methyl-D-aspartate (NMDA) receptor. The encoded protein is found primarily in motor neurons, where it forms a heterotetramer with GRIN1 to create an excitatory glycine receptor. Variations in this gene have been proposed to be linked to schizophrenia.
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