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Rabbit anti-Human GTF2E2 Polyclonal Antibody

The antibody against GTF2E2 was raised in rabbit using the Recombinant Human Transcription initiation factor IIE subunit beta protein (1-291AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

ADC-50613A

The antibody against GTF2E2 was raised in rabbit using the Recombinant Human Transcription initiation factor IIE subunit beta protein (1-291AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-50613A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGTF2E2
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Transcription initiation factor IIE subunit beta protein (1-291AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP29084
Background Information
  • Uniprot Id

    P29084

  • Target Species

    Human

  • Target Name

    GTF2E2

  • Target Full Name

    Transcription initiation factor IIE subunit beta

  • Target Function

    Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

  • Target Involvement

    Trichothiodystrophy 6, non-photosensitive (TTD6)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    TFIIE beta subunit family

  • Target Research Area

    Transcription

  • Target Synonyms

    FE; General transcription factor IIE subunit 2; General transcription factor IIE; polypeptide 2; beta 34kDa ; gtf2e2; T2EB_HUMAN; TF2E 2; TF2E2; TFIIE B; TFIIE-beta; Transcription initiation factor IIE beta subunit; Transcription initiation factor IIE subunit beta

  • Target Background

    The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer (and sometimes heterotetramer) of alpha and beta subunits. The protein encoded by this gene represents the beta subunit of TFIIE.

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