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The antibody against HAS3 was raised in rabbit using the Recombinant Human Hyaluronan synthase 3 protein (339-553AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
The antibody against HAS3 was raised in rabbit using the Recombinant Human Hyaluronan synthase 3 protein (339-553AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human thyroid tissue using HAS3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human cervical cancer using HAS3 Antibody at dilution of 1:1002
Immunofluorescent analysis of U251 cells using HAS3 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-45308A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HAS3 |
| Target Synonyms | HAS3; Hyaluronan synthase 3; Hyaluronate synthase 3; Hyaluronic acid synthase 3; HA synthase 3 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Hyaluronan synthase 3 protein (339-553AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O00219 |
Uniprot Id
O00219
Target Species
Human
Target Name
HAS3
Target Full Name
Hyaluronan synthase 3
Target Function
Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
NodC/HAS family
Target Synonyms
HAS3; Hyaluronan synthase 3; Hyaluronate synthase 3; Hyaluronic acid synthase 3; HA synthase 3
Target Background
The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants.
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