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Rabbit anti-Human HPN Polyclonal Antibody

The antibody against HPN was raised in rabbit using the Human Hpn as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein A purified. This antibody has been validated on ELISA, WB.

ADC-53098A

The antibody against HPN was raised in rabbit using the Human Hpn as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein A purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-53098A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHPN
Target SynonymsHPN; TMPRSS1; Serine protease hepsin; Transmembrane protease serine 1FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodProtein A purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman HpnTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP05981
Background Information
  • Uniprot Id

    P05981

  • Target Species

    Human

  • Target Name

    HPN

  • Target Full Name

    Serine protease hepsin

  • Target Function

    Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization.

  • Target Subcellular Location

    Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein.

  • Target Protein Families

    Peptidase S1 family

  • Target Tissue Specificity

    Detected in liver and kidney.

  • Target Synonyms

    HPN; TMPRSS1; Serine protease hepsin; Transmembrane protease serine 1

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