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The antibody against IGFALS was raised in rabbit using the Synthesized peptide derived from the Internal region of Human ALS. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against IGFALS was raised in rabbit using the Synthesized peptide derived from the Internal region of Human ALS. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of CoLo cells using ALS Polyclonal Antibody
| Cat.No | ADC-35294A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IGFALS |
| Target Synonyms | IGFALS antibody; ALSInsulin-like growth factor-binding protein complex acid labile subunit antibody; ALS antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human ALS. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P35858 |
Uniprot Id
P35858
Target Species
Human
Target Name
IGFALS
Target Full Name
Insulin-like growth factor-binding protein complex acid labile subunit
Target Function
Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.
Target Involvement
Acid-labile subunit deficiency (ACLSD)
Target Subcellular Location
Secreted, extracellular space.
Target Tissue Specificity
Plasma.
Target Synonyms
IGFALS; ALSInsulin-like growth factor-binding protein complex acid labile subunit; ALS
Target Background
The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.
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