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The antibody against IGFBP5 was raised in rabbit using the Recombinant protein of Human IGFBP5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against IGFBP5 was raised in rabbit using the Recombinant protein of Human IGFBP5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity purified. This antibody has been validated on ELISA, WB, IHC.
$398.00
Western blot analysis of extracts of HEK-293T cell lines, using IGFBP5 antibody.
| Cat.No | ADC-46248A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IGFBP5 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant protein of Human IGFBP5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P24593 |
Uniprot Id
P24593
Target Species
Human
Target Name
IGFBP5
Target Full Name
Insulin-like growth factor-binding protein 5
Target Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Target Subcellular Location
Secreted.
Target Tissue Specificity
Osteosarcoma, and at lower levels in liver, kidney and brain.
Target Research Area
Signal Transduction
Target Synonyms
IBP 5; IBP-5; IBP5; IBP5_HUMAN; IGF binding protein 5; IGF BP5; IGF-binding protein 5; IGFBP 5; IGFBP-5; IGFBP5; Insulin like growth factor binding protein 5; Insulin-like growth factor-binding protein 5
Target Background
Enables insulin-like growth factor I binding activity. Involved in several processes, including cellular response to cAMP; regulation of smooth muscle cell migration; and regulation of smooth muscle cell proliferation. Part of insulin-like growth factor ternary complex. Biomarker of pulmonary fibrosis.
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