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The antibody against IGHA2 was raised in rabbit using the Recombinant Human Immunoglobulin heavy constant alpha 2 protein (36-111AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against IGHA2 was raised in rabbit using the Recombinant Human Immunoglobulin heavy constant alpha 2 protein (36-111AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-04344A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IGHA2 |
| Target Synonyms | IGHA2Immunoglobulin heavy constant alpha 2 antibody; Ig alpha-2 chain C region antibody; Ig alpha-2 chain C region BUT antibody; Ig alpha-2 chain C region LAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Immunoglobulin heavy constant alpha 2 protein (36-111AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P01877 |
Uniprot Id
P01877
Target Species
Human
Target Name
IGHA2
Target Full Name
Immunoglobulin heavy constant alpha 2
Target Function
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. Ig alpha is the major immunoglobulin class in body secretions.
Target Subcellular Location
Secreted. Cell membrane.
Target Synonyms
IGHA2Immunoglobulin heavy constant alpha 2; Ig alpha-2 chain C region; Ig alpha-2 chain C region BUT; Ig alpha-2 chain C region LAN
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