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The antibody against INTS13 was raised in rabbit using the Recombinant Human Integrator complex subunit 13 protein (573-706AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against INTS13 was raised in rabbit using the Recombinant Human Integrator complex subunit 13 protein (573-706AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-04629A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | INTS13 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | FITC conjugated |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Integrator complex subunit 13 protein (573-706AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NVM9 |
Uniprot Id
Q9NVM9
Target Species
Human
Target Name
INTS13
Target Full Name
Integrator complex subunit 13
Target Function
Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
Asunder family
Target Tissue Specificity
Widely expressed. Tends to be up-regulated in seminomas compared to normal testis.
Target Synonyms
asun; ASUN_HUMAN; Cell cycle regulator Mat89Bb homolog; Chromosome 12 open reading frame 11; FLJ10630; FLJ10637; Germ cell tumor 1; NET48; Protein asunder homolog; Sarcoma antigen NY SAR 95; Sarcoma antigen NY-SAR-95
Target Background
Involved in regulation of mitotic cell cycle. Acts upstream of or within centrosome localization; mitotic spindle organization; and protein localization to nuclear envelope. Located in cytoplasm and nuclear body.
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