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The antibody against KCNIP4 was raised in rabbit using the Recombinant Human Kv channel-interacting protein 4 protein (1-250AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against KCNIP4 was raised in rabbit using the Recombinant Human Kv channel-interacting protein 4 protein (1-250AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human brain tissue using KCNIP4 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using KCNIP4 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-19698A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KCNIP4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Kv channel-interacting protein 4 protein (1-250AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6PIL6 |
Uniprot Id
Q6PIL6
Target Species
Human
Target Name
KCNIP4
Target Full Name
Kv channel-interacting protein 4
Target Function
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Modulates KCND3/Kv4.3 currents. Isoform 4 does not increase KCND2 expression at the cell membrane. Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.
Target Subcellular Location
Cell membrane; Peripheral membrane protein. Cytoplasm.; [Isoform 4]: Endoplasmic reticulum.
Target Protein Families
Recoverin family
Target Tissue Specificity
Predominantly expressed in brain.
Target Synonyms
A type potassium channel modulatory protein 4; A-type potassium channel modulatory protein 4; CALP; Calsenilin like protein; Calsenilin-like protein; HGNC:30083; KCHIP 4; KChIP4; KCIP4_HUMAN; KCNIP 4; Kcnip4; Kv channel interacting protein 4; Kv channel-interacting protein 4; MGC44947; Potassium channel interacting protein 4; Potassium channel-interacting protein 4
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