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The antibody against KCNK10 was raised in rabbit using the Synthetic Peptide as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against KCNK10 was raised in rabbit using the Synthetic Peptide as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen. This antibody has been validated on WB, IHC, ELISA.
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Western blot analysis of 1) Mouse BrainTissue, 2)Rat Brain Tissue, 3) Jurkat with KCNK10(TREK-2) Rabbit pAb diluted at 1:2,000.
Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using KCNK10 (TREK-2) Rabbit pAb diluted at 1:200.2
| Cat.No | ADC-13182A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KCNK10 |
| Target Synonyms | KCNK10; TREK2; Potassium channel subfamily K member 10; Outward rectifying potassium channel protein TREK-2; TREK-2 K(+ channel subunit | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthetic Peptide | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P57789 |
Uniprot Id
P57789
Target Species
Human
Target Name
KCNK10
Target Full Name
Potassium channel subfamily K member 10
Target Function
Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Two pore domain potassium channel (TC 1.A.1.8) family
Target Tissue Specificity
Abundantly expressed in pancreas and kidney and to a lower level in brain, testis, colon, and small intestine. Isoform b is strongly expressed in kidney (primarily in the proximal tubule) and pancreas, whereas isoform c is abundantly expressed in brain.
Target Synonyms
KCNK10; TREK2; Potassium channel subfamily K member 10; Outward rectifying potassium channel protein TREK-2; TREK-2 K(+ channel subunit
Target Background
The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
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