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The antibody against KIF24 was raised in rabbit using the Recombinant Human Kinesin-like protein KIF24 protein (1168-1368AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against KIF24 was raised in rabbit using the Recombinant Human Kinesin-like protein KIF24 protein (1168-1368AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human melanoma using KIF24 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human heart tissue using KIF24 Antibody at dilution of 1:1002
| Cat.No | ADC-19948A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KIF24 |
| Target Synonyms | bA571F15.4 antibody; C9orf48 antibody; Kif24 antibody; KIF24_HUMAN antibody; kinesin family member 24 antibody; Kinesin-like protein KIF24 antibody; RP11-571F15.7 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Kinesin-like protein KIF24 protein (1168-1368AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5T7B8 |
Uniprot Id
Q5T7B8
Target Species
Human
Target Name
KIF24
Target Full Name
Kinesin-like protein KIF24
Target Function
Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation. Following activation by NEK2 involved in disassembly of primary cilium during G2/M phase but does not disassemble fully formed ciliary axonemes. As cilium assembly and disassembly is proposed to coexist in a dynamic equilibrium may suppress nascent cilium assembly and, potentially, ciliar re-assembly in cells that have already disassembled their cilia ensuring the completion of cilium removal in the later stages of the cell cycle.
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Primarily localizes to the mother centriole/basal body and is either absent at daughter centriole.
Target Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
Target Synonyms
bA571F15.4; C9orf48; Kif24; KIF24_HUMAN; kinesin family member 24; Kinesin-like protein KIF24; RP11-571F15.7
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