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The antibody against KLF12 was raised in rabbit using the Human KLF12 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against KLF12 was raised in rabbit using the Human KLF12 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48159A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KLF12 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human KLF12 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y4X4 |
Uniprot Id
Q9Y4X4
Target Species
Human
Target Name
KLF12
Target Full Name
Krueppel-like factor 12
Target Function
Confers strong transcriptional repression to the AP-2-alpha gene. Binds to a regulatory element (A32) in the AP-2-alpha gene promoter.
Target Subcellular Location
Nucleus.
Target Protein Families
Sp1 C2H2-type zinc-finger protein family
Target Synonyms
2700063E05Rik; AI225908; AI315654; AP-2 repressor; AP-2rep; AP-2rep transcription factor; AP2REP; B130052C06Rik; D530033K05Rik; HSPC122; KLF12; KLF12 zinc finger transcriptional repressor; KLF12_HUMAN; Krueppel like factor 12; Krueppel-like factor 12; OTTHUMP00000018503; Transcriptional repressor AP 2rep ; Transcriptional repressor AP-2rep
Target Background
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
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