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The antibody against LAMTOR3 was raised in rabbit using the Recombinant Human Ragulator complex protein LAMTOR3 protein (1-124AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against LAMTOR3 was raised in rabbit using the Recombinant Human Ragulator complex protein LAMTOR3 protein (1-124AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human prostate tissue using LAMTOR3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using LAMTOR3 Antibody at dilution of 1:1002
| Cat.No | ADC-44342A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LAMTOR3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ragulator complex protein LAMTOR3 protein (1-124AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UHA4 |
Uniprot Id
Q9UHA4
Target Species
Human
Target Name
LAMTOR3
Target Full Name
Ragulator complex protein LAMTOR3
Target Function
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
Target Subcellular Location
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
LAMTOR3 family
Target Research Area
Signal Transduction
Target Synonyms
LAMTOR3; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3; LTOR3_HUMAN; MAP2K1IP1; MEK binding partner 1; MEK partner 1 ; MEK-binding partner 1; Mitogen activated protein kinase kinase 1 interacting protein 1; Mitogen-activated protein kinase kinase 1-interacting protein 1; Mitogen-activated protein kinase scaffold protein 1; Mp1; Ragulator complex protein LAMTOR3
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