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The antibody against LETMD1 was raised in rabbit using the Fusion protein of Human LETMD1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against LETMD1 was raised in rabbit using the Fusion protein of Human LETMD1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-29919A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LETMD1 |
| Target Synonyms | LETMD1LETM1 domain-containing protein 1 antibody; Cervical cancer 1 proto-oncogene protein p40 antibody; Cervical cancer proto-oncogene 2 protein antibody; HCCR-1 antibody; HCRR-2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human LETMD1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6P1Q0 |
Uniprot Id
Q6P1Q0
Target Species
Human
Target Name
LETMD1
Target Full Name
LETM1 domain-containing protein 1
Target Function
Involved in tumorigenesis and may function as a negative regulator of the p53/TP53.
Target Subcellular Location
Mitochondrion outer membrane; Single-pass membrane protein.
Target Tissue Specificity
Kidney, liver, skeletal muscle, heart and brain. Overexpressed in various tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon and uterine cervix.
Target Synonyms
LETMD1LETM1 domain-containing protein 1; Cervical cancer 1 proto-oncogene protein p40; Cervical cancer proto-oncogene 2 protein; HCCR-1; HCRR-2
Target Background
This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene.
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