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The antibody against LHB was raised in rabbit using the Recombinant Human Lutropin subunit beta protein (21-141AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against LHB was raised in rabbit using the Recombinant Human Lutropin subunit beta protein (21-141AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human placenta tissue using LHB Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using LHB Antibody at dilution of 1:1002
| Cat.No | ADC-50209A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LHB |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Lutropin subunit beta protein (21-141AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P01229 |
Uniprot Id
P01229
Target Species
Human
Target Name
LHB
Target Full Name
Lutropin subunit beta
Target Function
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
Target Involvement
Hypogonadotropic hypogonadism 23 without anosmia (HH23)
Target Subcellular Location
Secreted.
Target Protein Families
Glycoprotein hormones subunit beta family
Target Tissue Specificity
Pituitary gland.
Target Synonyms
LHB; CGB4; HH23; LSH-B; LSH-beta; lutropin subunit beta; Lutropin subunit beta
Target Background
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
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