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The antibody against LPGAT1 was raised in rabbit using the Recombinant Human Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 protein (151-341AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against LPGAT1 was raised in rabbit using the Recombinant Human Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 protein (151-341AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human liver cancer using LPGAT1 Antibody at dilution of 1:100
| Cat.No | ADC-19157A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LPGAT1 |
| Target Synonyms | LPGAT1; FAM34A; KIAA0205; Acyl-CoA:lysophosphatidylglycerol acyltransferase 1; Acyl-CoA:monoacylglycerol acyltransferase LPGAT1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 protein (151-341AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q92604 |
Uniprot Id
Q92604
Target Species
Human
Target Name
LPGAT1
Target Full Name
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1
Target Function
Catalyzes the transfert of an acyl group from an acyl-CoA to a lysophosphatidylglycerol (LPG) leading to biosynthesis of phosphatidylglycerol, a precursor for cardiolipin synthesis. Uses various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor. In vitro can also catalyzes the transfert of an acyl group from an acyl-CoA to a monoacylglycerol leading to diacylglycerol synthesis, a precursor of triacylglycerol and plays a role in hepatic triacylglycerol synthesis and secretion. Prefers the sn-2-monoacylglycerol to rac-1-monoacylglycerol as acyl acceptor.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
1-acyl-sn-glycerol-3-phosphate acyltransferase family
Target Tissue Specificity
Highly expressed in liver and placenta. Also expressed in peripheral blood, lung, kidney and brain. Detected at lower levels in colon.
Target Synonyms
LPGAT1; FAM34A; KIAA0205; Acyl-CoA:lysophosphatidylglycerol acyltransferase 1; Acyl-CoA:monoacylglycerol acyltransferase LPGAT1
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