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The antibody against LPIN2 was raised in rabbit using the Human LPIN2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against LPIN2 was raised in rabbit using the Human LPIN2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48079A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LPIN2 |
| Target Synonyms | KIAA0249 antibody; Lipin-2 antibody; Lipin2 antibody; LPIN 2 antibody; LPIN2 antibody; LPIN2_HUMAN antibody; OTTHUMP00000162242 antibody; Phosphatidate phosphatase LPIN2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human LPIN2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q92539 |
Uniprot Id
Q92539
Target Species
Human
Target Name
LPIN2
Target Full Name
Phosphatidate phosphatase LPIN2
Target Function
Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Plays important roles in controlling the metabolism of fatty acids at different levels. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.
Target Involvement
Majeed syndrome (MJDS)
Target Subcellular Location
Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum membrane.
Target Protein Families
Lipin family
Target Tissue Specificity
Expressed in liver, lung, kidney, placenta, spleen, thymus, lymph node, prostate, testes, small intestine, and colon.
Target Synonyms
KIAA0249; Lipin-2; Lipin2; LPIN 2; LPIN2; LPIN2_HUMAN; OTTHUMP00000162242; Phosphatidate phosphatase LPIN2
Target Background
Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance.
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