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Rabbit anti-Human LRRTM4 Polyclonal Antibody

The antibody against LRRTM4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 310-420 of human LRRTM4 (NP_001269857.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10035A

The antibody against LRRTM4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 310-420 of human LRRTM4 (NP_001269857.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-10035A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLRRTM4
Target SynonymsLRRTM4FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesRat brain, Mouse brain, U-87MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 310-420 of human LRRTM4 (NP_001269857.1).Target SpeciesHuman
Immunogen SequenceSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKHIQGEKVSDAVETYNICSEVQVVNTERSHLVPQTPQKPLIIPRPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHUniprot IDQ86VH4
Background Information
  • Uniprot Id

    Q86VH4

  • Target Species

    Human

  • Target Name

    LRRTM4

  • Target Full Name

    Leucine-rich repeat transmembrane neuronal protein 4

  • Target Function

    May play a role in the development and maintenance of the vertebrate nervous system. Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein.

  • Target Protein Families

    LRRTM family

  • Target Tissue Specificity

    Expressed in neuronal tissues.

  • Target Synonyms

    FLJ12568; Leucine rich repeat transmembrane neuronal 4; Leucine rich repeat transmembrane neuronal 4 protein ; Leucine rich repeat transmembrane neuronal protein 4; Leucine-rich repeat transmembrane neuronal protein 4; LRRT4_HUMAN; Lrrtm4; MGC120633; MGC120636; OTTHUMP00000202553 ; OTTHUMP00000202556

  • Target Background

    Predicted to enable heparan sulfate proteoglycan binding activity. Predicted to be involved in regulation of synapse assembly. Predicted to act upstream of or within AMPA glutamate receptor clustering; positive regulation of synapse assembly; and regulation of presynaptic membrane organization. Predicted to be located in postsynaptic membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in extracellular matrix; extracellular space; and glutamatergic synapse. Predicted to be integral component of postsynaptic density membrane.

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