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The antibody against LRRTM4 was raised in rabbit using the Recombinant Human Leucine-rich repeat transmembrane neuronal protein 4 protein (259-419AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against LRRTM4 was raised in rabbit using the Recombinant Human Leucine-rich repeat transmembrane neuronal protein 4 protein (259-419AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human brain tissue using LRRTM4 Antibody at dilution of 1:1002
| Cat.No | ADC-14286A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LRRTM4 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Leucine-rich repeat transmembrane neuronal protein 4 protein (259-419AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86VH4 |
Uniprot Id
Q86VH4
Target Species
Human
Target Name
LRRTM4
Target Full Name
Leucine-rich repeat transmembrane neuronal protein 4
Target Function
May play a role in the development and maintenance of the vertebrate nervous system. Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein.
Target Protein Families
LRRTM family
Target Tissue Specificity
Expressed in neuronal tissues.
Target Synonyms
FLJ12568; Leucine rich repeat transmembrane neuronal 4; Leucine rich repeat transmembrane neuronal 4 protein ; Leucine rich repeat transmembrane neuronal protein 4; Leucine-rich repeat transmembrane neuronal protein 4; LRRT4_HUMAN; Lrrtm4; MGC120633; MGC120636; OTTHUMP00000202553 ; OTTHUMP00000202556
Target Background
Predicted to enable heparan sulfate proteoglycan binding activity. Predicted to be involved in regulation of synapse assembly. Predicted to act upstream of or within AMPA glutamate receptor clustering; positive regulation of synapse assembly; and regulation of presynaptic membrane organization. Predicted to be located in postsynaptic membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in extracellular matrix; extracellular space; and glutamatergic synapse. Predicted to be integral component of postsynaptic density membrane.
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