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The antibody against LRTOMT was raised in rabbit using the Recombinant Human Transmembrane O-methyltransferase protein (31-264AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against LRTOMT was raised in rabbit using the Recombinant Human Transmembrane O-methyltransferase protein (31-264AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
Immunofluorescent analysis of HepG2 cells using LRTOMT Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
| Cat.No | ADC-51005A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LRTOMT |
| Target Synonyms | TOMT; COMT2; LRTOMT; PP7517; Transmembrane O-methyltransferase; Catechol O-methyltransferase 2; Protein LRTOMT2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transmembrane O-methyltransferase protein (31-264AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WZ04 |
Uniprot Id
Q8WZ04
Target Species
Human
Target Name
LRTOMT
Target Full Name
Transmembrane O-methyltransferase
Target Function
Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Required for auditory function. Component of the cochlear hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity.
Target Involvement
Deafness, autosomal recessive, 63 (DFNB63)
Target Subcellular Location
[Isoform 1]: Membrane; Single-pass membrane protein.; [Isoform 2]: Cytoplasm. Endoplasmic reticulum.
Target Protein Families
Class I-like SAM-binding methyltransferase superfamily, Cation-dependent O-methyltransferase family
Target Synonyms
TOMT; COMT2; LRTOMT; PP7517; Transmembrane O-methyltransferase; Catechol O-methyltransferase 2; Protein LRTOMT2
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