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Rabbit anti-Human LUM Polyclonal Antibody

The antibody against LUM was raised in rabbit using the Human LUM as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-52836A

The antibody against LUM was raised in rabbit using the Human LUM as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-52836A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLum
Target SynonymsKeratan sulfate proteoglycan lumican antibody; KSPG lumican antibody; LDC antibody; LUM antibody; LUM_HUMAN antibody; Lumican antibody; Lumican precursor antibody; SLRR2D antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman LUMTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP51884
Background Information
  • Uniprot Id

    P51884

  • Target Species

    Human

  • Target Name

    LUM

  • Target Full Name

    Lumican

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix.

  • Target Protein Families

    Small leucine-rich proteoglycan (SLRP) family, SLRP class II subfamily

  • Target Tissue Specificity

    Cornea and other tissues.

  • Target Synonyms

    Keratan sulfate proteoglycan lumican; KSPG lumican; LDC; LUM; LUM_HUMAN; Lumican; Lumican precursor; SLRR2D

  • Target Background

    This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

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