Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against MBNL3 was raised in rabbit using the Recombinant Human Muscleblind-like protein 3 protein (116-211AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against MBNL3 was raised in rabbit using the Recombinant Human Muscleblind-like protein 3 protein (116-211AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-04635A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MBNL3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Muscleblind-like protein 3 protein (116-211AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NUK0 |
Uniprot Id
Q9NUK0
Target Species
Human
Target Name
MBNL3
Target Full Name
Muscleblind-like protein 3
Target Function
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.
Target Subcellular Location
Nucleus. Cytoplasm. Note=Greater concentration in the nucleus. In both DM1 and DM2 patients, colocalizes with nuclear foci of retained expanded-repeat transcripts.
Target Protein Families
Muscleblind family
Target Tissue Specificity
Highly expressed in the placenta.
Target Synonyms
A530038J18Rik; AI661274; CHCR; Cys3His CCG1 required protein; Cys3His CCG1-required protein; E430034C16Rik; MBLX; MBLX39; MBNL 3; Mbnl3; MBNL3_HUMAN; MBXL; Muscleblind like 3; Muscleblind like protein 3; Muscleblind like splicing regulator 3; Muscleblind like X linked protein; Muscleblind-like protein 3; Muscleblind-like X-linked protein; OTTMUSP00000019072; OTTMUSP00000019073; OTTMUSP00000019074; Protein HCHCR; RP23-98P13.1
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
