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The antibody against ME1 was raised in rabbit using the Human ME1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against ME1 was raised in rabbit using the Human ME1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-48006A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ME1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human ME1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P48163 |
Uniprot Id
P48163
Target Species
Human
Target Name
ME1
Target Full Name
NADP-dependent malic enzyme
Target Subcellular Location
Cytoplasm.
Target Protein Families
Malic enzymes family
Target Tissue Specificity
Expressed in all tissues tested including liver, placenta and white adipose tissue.
Target Synonyms
Cytosolic malic enzyme 1 ; HUMNDME; Malate dehydrogenase ; Malic enzyme 1; Malic enzyme 1; NADP(+) dependent; cytosolic; Malic enzyme 1; soluble ; Malic enzyme; cytoplasmic ; MAOX_HUMAN; ME1; MES; NADP dependent malic enzyme; NADP ME; NADP-dependent malic enzyme; NADP-ME; Pyruvic malic carboxylase
Target Background
This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
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