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The antibody against MIA2 was raised in rabbit using the Synthesized peptide derived from MIA2 at AA range: 361-410 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against MIA2 was raised in rabbit using the Synthesized peptide derived from MIA2 at AA range: 361-410 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of HEPG2 cells using MIA2 Polyclonal Antibody diluted at 1:500. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:2002
Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:2003
| Cat.No | ADC-13097A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MIA2 |
| Target Synonyms | FLJ22404 antibody; Melanoma inhibitory activity 2 antibody; Melanoma inhibitory activity protein 2 antibody; Mia2 antibody; MIA2_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from MIA2 at AA range: 361-410 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96PC5 |
Uniprot Id
Q96PC5
Target Species
Human
Target Name
MIA2
Target Full Name
Melanoma inhibitory activity protein 2
Target Function
Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum. Thereby, may play a role in cholesterol and triglyceride homeostasis. Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Target Protein Families
MIA/OTOR family
Target Tissue Specificity
Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis. Isoform 1 is specifically expressed in lung, testis, small intestine, colon, pancreas, kidney, liver and prostate
Target Synonyms
FLJ22404; Melanoma inhibitory activity 2; Melanoma inhibitory activity protein 2; Mia2; MIA2_HUMAN
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