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The antibody against MPC1 was raised in rabbit using the Synthesized peptide derived from internal of Human BRP44L. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against MPC1 was raised in rabbit using the Synthesized peptide derived from internal of Human BRP44L. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
$297.00
Western blot analysis of extracts from COLO cells and HeLa cells, using BRP44L antibody.
Immunohistochemistry analysis of paraffin-embedded human heart tissue using BRP44L antibody.2
Immunofluorescence analysis of A549 cells, using BRP44L antibody.3
| Cat.No | ADC-41405A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MPC1 |
| Target Synonyms | 1 antibody, mitochondrial | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human BRP44L. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y5U8 |
Uniprot Id
Q9Y5U8
Target Species
Human
Target Name
MPC1
Target Full Name
Mitochondrial pyruvate carrier 1
Target Function
Mediates the uptake of pyruvate into mitochondria.
Target Involvement
Mitochondrial pyruvate carrier deficiency (MPYCD)
Target Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Target Protein Families
Mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family
Target Synonyms
MPYCD; BRP44L; CGI-129; SLC54A1; MPC1
Target Background
The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene.
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