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The antibody against MRPL44 was raised in rabbit using the Synthesized peptide derived from internal of Human MRPL44. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against MRPL44 was raised in rabbit using the Synthesized peptide derived from internal of Human MRPL44. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
$297.00
Western blot analysis of extracts from COS-7 cells, using MRPL44 antibody.
Immunohistochemistry analysis of paraffin-embedded human heart tissue using MRPL44 antibody.2
Immunofluorescence analysis of HuvEc cells, using MRPL44 antibody.3
| Cat.No | ADC-41569A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPL44 |
| Target Synonyms | MRPL44 antibody; 39S ribosomal protein L44 antibody; mitochondrial antibody; L44mt antibody; MRP-L44 antibody; EC 3.1.26.- antibody; Mitochondrial large ribosomal subunit protein mL44 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human MRPL44. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H9J2 |
Uniprot Id
Q9H9J2
Target Species
Human
Target Name
MRPL44
Target Full Name
Large ribosomal subunit protein mL44
Target Function
Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome.
Target Involvement
Combined oxidative phosphorylation deficiency 16 (COXPD16)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Ribonuclease III family, Mitochondrion-specific ribosomal protein mL44 subfamily
Target Synonyms
MRPL44; 39S ribosomal protein L44; mitochondrial; L44mt; MRP-L44; EC 3.1.26.-; Mitochondrial large ribosomal subunit protein mL44
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
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