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Rabbit anti-Human MRPL52 Polyclonal Antibody

The antibody against MRPL52 was raised in rabbit using the Human MRPL52 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-52695A

The antibody against MRPL52 was raised in rabbit using the Human MRPL52 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-52695A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMRPL52
Target Synonyms39S ribosomal protein L52 antibody; L52mt antibody; mitochondrial antibody; MRP-L52 antibody; Mrpl52 antibody; RM52_HUMAN antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman MRPL52Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ86TS9
Background Information
  • Uniprot Id

    Q86TS9

  • Target Species

    Human

  • Target Name

    MRPL52

  • Target Full Name

    Large ribosomal subunit protein mL52

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Mitochondrion-specific ribosomal protein mL52 family

  • Target Synonyms

    39S ribosomal protein L52; L52mt; mitochondrial; MRP-L52; Mrpl52; RM52_HUMAN

  • Target Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which has no bacterial homolog. Multiple transcript variants encoding different protein isoforms were identified through sequence analysis.

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