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Rabbit anti-Human MRPS14 Polyclonal Antibody

The antibody against MRPS14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human MRPS14 (NP_071383.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-05011A

The antibody against MRPS14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human MRPS14 (NP_071383.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-05011A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMRPS14
Target SynonymsS14mt; COXPD38; MRP-S14; HSMRPS14; DJ262D12.2; MRPS14FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heart, Mouse kidney, BxPC-3, Mouse liver, U-251MGApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human MRPS14 (NP_071383.1).Target SpeciesHuman
Immunogen SequenceMAAFMLGSLLRTFKQMVPSSASGQVRSHYVDWRMWRDVKRRKMAYEYADERLRINSLRKNTILPKILQDVADEEIAALPRDSCPVRIRNRCVMTSRPRGVKRRWRLSRIVFRHLADHGQLSGIQRATWUniprot IDO60783
Background Information
  • Uniprot Id

    O60783

  • Target Species

    Human

  • Target Name

    MRPS14

  • Target Full Name

    Small ribosomal subunit protein uS14m

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Universal ribosomal protein uS14 family

  • Target Synonyms

    MRPS14; 28S ribosomal protein S14; mitochondrial; MRP-S14; S14mt; Mitochondrial small ribosomal subunit protein uS14m

  • Target Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S14P family. Alternative splicing results in multiple transcript variants.

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