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The antibody against MSI1 was raised in rabbit using the Recombinant Human RNA-binding protein Musashi homolog 1 protein (221-347AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against MSI1 was raised in rabbit using the Recombinant Human RNA-binding protein Musashi homolog 1 protein (221-347AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-07319A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MSI1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human RNA-binding protein Musashi homolog 1 protein (221-347AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43347 |
Uniprot Id
O43347
Target Species
Human
Target Name
MSI1
Target Full Name
RNA-binding protein Musashi homolog 1
Target Function
RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
Musashi family
Target Tissue Specificity
Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
Target Synonyms
Msi 1; Msi1; MSI1H_HUMAN; Musashi homolog 1; Musashi RNA binding protein 1; Musashi-1; Musashi1; RNA binding protein Musashi homolog 1; RNA-binding protein Musashi homolog 1
Target Background
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.
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