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The antibody against MSRB3 was raised in rabbit using the Recombinant Human Methionine-R-sulfoxide reductase B3 protein (1-185AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against MSRB3 was raised in rabbit using the Recombinant Human Methionine-R-sulfoxide reductase B3 protein (1-185AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-16774A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MSRB3 |
| Target Synonyms | Deafness | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Methionine-R-sulfoxide reductase B3 protein (1-185AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IXL7 |
Uniprot Id
Q8IXL7
Target Species
Human
Target Name
MSRB3
Target Full Name
Methionine-R-sulfoxide reductase B3
Target Function
Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing.
Target Involvement
Deafness, autosomal recessive, 74 (DFNB74)
Target Subcellular Location
[Isoform 1]: Endoplasmic reticulum.; [Isoform 2]: Mitochondrion.
Target Protein Families
MsrB Met sulfoxide reductase family
Target Tissue Specificity
Widely expressed.
Target Research Area
Signal Transduction
Target Synonyms
Deafness, Autosomal Recessive 74; DFNB74; FLJ36866; Methionine R sulfoxide reductase B mitochondrial; Methionine sulfoxide reductase B3; Methionine-R-sulfoxide reductase B3; MsrB3; MSRB3_HUMAN
Target Background
The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula.
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