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The antibody against MSTN was raised in rabbit using the Human MSTN as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against MSTN was raised in rabbit using the Human MSTN as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-52677A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MSTN |
| Target Synonyms | Cmpt antibody; GDF-8 antibody; GDF8_HUMAN antibody; Growth/differentiation factor 8 antibody; MSLHP antibody; MSTN antibody; MSTN myostatin antibody; Myostatin antibody; Myostatin Propeptide antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human MSTN | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14793 |
Uniprot Id
O14793
Target Species
Human
Target Name
MSTN
Target Full Name
Growth/differentiation factor 8
Target Function
Acts specifically as a negative regulator of skeletal muscle growth.
Target Involvement
Muscle hypertrophy (MSLHP)
Target Subcellular Location
Secreted.
Target Protein Families
TGF-beta family
Target Research Area
Signal Transduction
Target Synonyms
Cmpt; GDF-8; GDF8_HUMAN; Growth/differentiation factor 8; MSLHP; MSTN; MSTN myostatin; Myostatin; Myostatin Propeptide
Target Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.
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