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The antibody against MTA3 was raised in rabbit using the Human MTA3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against MTA3 was raised in rabbit using the Human MTA3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-47915A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MTA3 |
| Target Synonyms | 1110002J22Rik antibody; fj99h01 antibody; KIAA1266 antibody; Metastasis associated 1 family, member 3 antibody; Metastasis associated 3 antibody; Metastasis associated family, member 3 antibody; Metastasis associated gene 3 antibody; Metastasis associated gene family, member 3 antibody; Mta3 metastasis associated 3 antibody; MTA3_HUMAN antibody; wu:fj99h01 antibody; zgc:56396 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human MTA3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BTC8 |
Uniprot Id
Q9BTC8
Target Species
Human
Target Name
MTA3
Target Full Name
Metastasis-associated protein MTA3
Target Function
Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expressed in germinal centers of lymphoid tissues. No expression in nonepithelial cells.
Target Synonyms
1110002J22Rik; fj99h01; KIAA1266; Metastasis associated 1 family, member 3; Metastasis associated 3; Metastasis associated family, member 3; Metastasis associated gene 3; Metastasis associated gene family, member 3; Metastasis associated protein MTA3; Metastasis-associated protein MTA3; MGC56396; MGC77410; mKIAA1266; mta1; Mta3; MTA3 metastasis associated 1 family, member 3; Mta3 metastasis associated 3; MTA3_HUMAN; wu:fj99h01; zgc:56396
Target Background
Predicted to enable histone deacetylase binding activity; transcription coactivator activity; and transcription corepressor activity. Involved in negative regulation of transcription, DNA-templated. Located in nucleoplasm. Part of NuRD complex.
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