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The antibody against NCAPG was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human hCAP-G. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against NCAPG was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human hCAP-G. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
| Cat.No | ADC-34153A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NCAPG |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human hCAP-G. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BPX3 |
Uniprot Id
Q9BPX3
Target Species
Human
Target Name
NCAPG
Target Full Name
Condensin complex subunit 3
Target Function
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Target Subcellular Location
Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Target Protein Families
CND3 (condensin subunit 3) family
Target Tissue Specificity
Highly expressed in testis.
Target Synonyms
CAPG; CHCG; Chromosome associated protein G; Chromosome condensation protein G; Chromosome-associated protein G; CND3_HUMAN; Condensin complex subunit 3; Condensin subunit CAP G; Condensin subunit CAP-G; HCAP G; hCAP-G; Melanoma antigen NY MEL 3; Melanoma antigen NY-MEL-3; NCAPG; Non SMC condensin I complex subunit G; Non-SMC condensin I complex subunit G; NY MEL 3; XCAP G homolog; XCAP-G homolog
Target Background
This gene encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There are pseudogenes for this gene on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants.
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