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The antibody against NDNF was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human NDNF (NP_078850.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NDNF was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human NDNF (NP_078850.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05366A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NDNF |
| Target Synonyms | HH25; NORD; C4orf31; NDNF | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human NDNF (NP_078850.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8TB73 | Immunogen Sequence |
Uniprot Id
Q8TB73
Target Species
Human
Target Name
NDNF
Target Full Name
Protein NDNF
Target Function
Secretory protein that plays a role in various cellular processes. Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus. Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system. May also act through the regulation of growth factors activity and downstream signaling. Also regulates extracellular matrix assembly and cell adhesiveness. Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms
Target Subcellular Location
Secreted.
Target Tissue Specificity
Expressed in neurons along the gonadotropin-releasing hormone (GnRH) expressing neurons migratory route.
Target Synonyms
C4orf31; Fibronectin type III domain containing protein C4orf31; NDNF; NDNF_HUMAN; Neuron-derived neurotrophic factor; PRO6487; Protein NDNF; UNQ2748
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