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The antibody against NEUROD2 was raised in rabbit using the Synthesized peptide derived from internal of Human NDF2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against NEUROD2 was raised in rabbit using the Synthesized peptide derived from internal of Human NDF2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from COLO cells, Jurkat cells and 293 cells, using NDF2 antibody.
| Cat.No | ADC-41944A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NEUROD2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human NDF2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q15784 |
Uniprot Id
Q15784
Target Species
Human
Target Name
NEUROD2
Target Full Name
Neurogenic differentiation factor 2
Target Function
Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections; involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter.
Target Subcellular Location
Nucleus.
Target Synonyms
bHLHa1; class A basic helix loop helix protein 1; Class A basic helix-loop-helix protein 1; NDF2_HUMAN; NDR2; NDRF; neuroD related factor; NeuroD-related factor; NeuroD2; neurogenic basic helix loop helix protein; neurogenic differentiation 2; Neurogenic differentiation factor 2; neuronal differentiation 2
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