Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against NFATC3 was raised in rabbit using the Peptide sequence around phosphorylation site of Serine 165(S-P-S(p)-P-A) derived from Human NFAT4. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi This antibody has been validated on ELISA, WB.
The antibody against NFATC3 was raised in rabbit using the Peptide sequence around phosphorylation site of Serine 165(S-P-S(p)-P-A) derived from Human NFAT4. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi This antibody has been validated on ELISA, WB.
$360.00
Western blot analysis of extracts from Hela cells using NFAT4 (Phospho-Ser165) Antibody.The lane on the right is treated with the antigen-specific peptide.
| Cat.No | ADC-43002A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NFATC3 |
| Target Synonyms | calcineurin dependent 3 antibody; Nuclear factor of activated T-cells antibody; T cell transcription factor NFAT4 antibody; T-cell transcription factor NFAT4 antibody, cytoplasmic, cytoplasmic 3 antibody; nuclear factor of activated T cells | Form | Liquid |
| Species Reactivity | Human, Mouse | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+) |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Peptide sequence around phosphorylation site of Serine 165(S-P-S(p)-P-A) derived from Human NFAT4. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q12968 |
Uniprot Id
Q12968
Target Species
Human
Target Name
NFATC3
Target Full Name
Nuclear factor of activated T-cells, cytoplasmic 3
Target Function
Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2. Along with NFATC4, involved in embryonic heart development.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.
Target Tissue Specificity
Isoform 1 is predominantly expressed in thymus and is also found in peripheral blood leukocytes and kidney. Isoform 2 is predominantly expressed in skeletal muscle and is also found in thymus, kidney, testis, spleen, prostate, ovary, small intestine, hear
Target Synonyms
C80703; cytoplasmic 3; D8Ertd281e; NF AT4; NF ATc3; NF-AT4; NF-ATc3; NFAC3_HUMAN; NFAT4; NFATc3; NFATx; Nuclear factor of activated T cells, cytoplasmic 3; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3; Nuclear factor of activated T-cells; T cell transcription factor NFAT4; T-cell transcription factor NFAT4
Target Background
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
