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The antibody against NFE2L3 was raised in rabbit using the Recombinant Human Nuclear factor erythroid 2-related factor 3 protein (132-260AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against NFE2L3 was raised in rabbit using the Recombinant Human Nuclear factor erythroid 2-related factor 3 protein (132-260AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-07378A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NFE2L3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Nuclear factor erythroid 2-related factor 3 protein (132-260AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y4A8 |
Uniprot Id
Q9Y4A8
Target Species
Human
Target Name
NFE2L3
Target Full Name
Nuclear factor erythroid 2-related factor 3
Target Function
Activates erythroid-specific, globin gene expression.
Target Subcellular Location
Nucleus.
Target Protein Families
BZIP family, CNC subfamily
Target Tissue Specificity
Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas.
Target Synonyms
NFE2L3; NRF3; Nuclear factor erythroid 2-related factor 3; NF-E2-related factor 3; NFE2-related factor 3; Nuclear factor; erythroid derived 2; like 3
Target Background
This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.
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