Rabbit anti-Human NODAL Polyclonal Antibody

The antibody against NODAL was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 198-347 of human NODAL (NP_060525.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10684A

Number

Cat.No	ADA-10684A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	NODAL
Target Synonyms	HTX5; NODAL	Form	Liquid
Species Reactivity	Human, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T, HepG2, Rat liver, SH-SY5Y	Application	ELISA, WB

Cat.No

ADA-10684A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

NODAL

Target Synonyms

HTX5; NODAL

Form

Liquid

Species Reactivity

Human, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T, HepG2, Rat liver, SH-SY5Y

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 198-347 of human NODAL (NP_060525.3).	Target Species	Human
Immunogen Sequence	SNLSQEQRQLGGSTLLWEAESSWRAQEGQLSWEWGKRHRRHHLPDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYVDNGRVLLDHHKDMIVEECGCL	Uniprot ID	Q96S42

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 198-347 of human NODAL (NP_060525.3).

Target Species

Human

Immunogen Sequence

SNLSQEQRQLGGSTLLWEAESSWRAQEGQLSWEWGKRHRRHHLPDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYVDNGRVLLDHHKDMIVEECGCL

Uniprot ID

Q96S42

Background Information

Uniprot Id

Q96S42
Target Species

Human
Target Name

NODAL
Target Full Name

Nodal homolog
Target Function

Essential for mesoderm formation and axial patterning during embryonic development.
Target Involvement

Heterotaxy, visceral, 5, autosomal (HTX5)
Target Subcellular Location

Secreted.
Target Protein Families

TGF-beta family
Target Synonyms

HTX5; MGC138230; Nodal; Nodal Growth Differentiation Factor; nodal homolog (mouse); Nodal homolog; Nodal; Mouse; Homolog; NODAL_HUMAN
Target Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.

Rabbit anti-Human NODAL Polyclonal Antibody

Specifications

Immunogen Information

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