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Rabbit anti-Human NRD1 Polyclonal Antibody

The antibody against NRDC was raised in rabbit using the Human NRD1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-47774A

The antibody against NRDC was raised in rabbit using the Human NRD1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-47774A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNRDC
Target SynonymsNRDC antibody; NRD1 antibody; Nardilysin antibody; EC 3.4.24.61 antibody; N-arginine dibasic convertase antibody; NRD convertase antibody; NRD-C antibody; Nardilysin convertase antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman NRD1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO43847
Background Information
  • Uniprot Id

    O43847

  • Target Species

    Human

  • Target Name

    NRDC

  • Target Full Name

    Nardilysin

  • Target Function

    Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.

  • Target Protein Families

    Peptidase M16 family

  • Target Tissue Specificity

    Primarily in adult heart, skeletal muscle, and testis and at much lower levels in other tissues.

  • Target Synonyms

    NRDC; NRD1; Nardilysin; EC 3.4.24.61; N-arginine dibasic convertase; NRD convertase; NRD-C; Nardilysin convertase

  • Target Background

    This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.

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