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The antibody against NT5C3A was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human NT5C3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
The antibody against NT5C3A was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human NT5C3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
$167.00
| Cat.No | ADC-32724A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NT5C3A |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the N-terminal region of Human NT5C3. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H0P0 |
Uniprot Id
Q9H0P0
Target Species
Human
Target Name
NT5C3A
Target Full Name
Cytosolic 5'-nucleotidase 3A
Target Function
Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP). CMP seems to be the preferred substrate.
Target Involvement
P5N deficiency (P5ND)
Target Subcellular Location
Cytoplasm.; [Isoform 2]: Endoplasmic reticulum.
Target Protein Families
Pyrimidine 5'-nucleotidase family
Target Tissue Specificity
Isoforms 1, 3 and 4 are expressed in reticulocytes. Isoform 4 is hardly detectable in bone marrow and fetal liver.
Target Synonyms
5NT3A_HUMAN; cN III ; cN-III; cNIII ; Cytosolic 5' nucleotidase 3; Cytosolic 5' nucleotidase III; Cytosolic 5''-nucleotidase 3; Cytosolic 5''-nucleotidase 3A; Cytosolic 5''-nucleotidase III; NT5C3; Nt5c3a; p36; P5''N-1; P5'N 1 ; P5'N1 ; P5N 1 ; P5N-1; P5N1 ; PN I ; PN-I; PNI ; PSN1 ; Pyrimidine 5' nucleotidase 1; Pyrimidine 5''-nucleotidase 1; UMPH ; UMPH1 ; Uridine 5' monophosphate hydrolase 1; Uridine 5''-monophosphate hydrolase 1
Target Background
This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4.
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