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The antibody against NTN4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 290-520 of human NTN4 (NP_067052.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NTN4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 290-520 of human NTN4 (NP_067052.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11454A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NTN4 |
| Target Synonyms | PRO3091; NTN4 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat heart, A-549 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 290-520 of human NTN4 (NP_067052.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9HB63 | Immunogen Sequence |
Uniprot Id
Q9HB63
Target Species
Human
Target Name
NTN4
Target Full Name
Netrin-4
Target Function
May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants.
Target Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Target Tissue Specificity
Expressed in kidney, spleen, mammary gland, aorta, heart, ovary, prostate and fetal spleen.
Target Research Area
Neuroscience
Target Synonyms
Beta netrin; Beta-netrin; FLJ23180; Hepar derived netrin like protein; Hepar-derived netrin-like protein; NET4_HUMAN; Netrin-4; Netrin4; NTN 4; NTN4; PRO3091
Target Background
This gene encodes a member of the netrin family of proteins, which function in various biological processes including axon guidance, tumorogenesis, and angiogenesis. Netrins are laminin-related proteins that have an N-terminal laminin-type domain, epidermal growth factor-like repeat domain, and a positively charged heparin-binding domain at the C-terminus. The protein encoded by this gene is involved in processes including neurite growth and migration, angiogenesis and mural cell adhesion to endothelial cells. Alternative splicing results in multiple transcript variants.
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